Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI)
ISOXSUPRINE HYDROCHLORIDE
CAS: 579-56-6
Molecular Formula: C18H24ClNO3
Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI) - Names and Identifiers
| Name | ISOXSUPRINE HYDROCHLORIDE |
| Synonyms | vasoplex vasodilan Isoxsuprine ISOXSUPRINE HYDROCHLORIDE 1-(p-Hydroxyphenyl)-2-(1'-methyl-2'-phenoxy)ethylaminopropanol-1 hydrochloride 4-Hydroxy-α-[1-[(1-Methyl-2-phenoxyethyl)aMino]ethyl]benzeneMethanol Hydrochloride Benzenemethanol, 4-hydroxy-.alpha.-1-(1-methyl-2-phenoxyethyl)aminoethyl-, hydrochloride Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI) Benzenemethanol, 4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (9CI) |
| CAS | 579-56-6 |
| EINECS | 209-443-6 |
Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI) - Physico-chemical Properties
| Molecular Formula | C18H24ClNO3 |
| Molar Mass | 337.84 |
| Melting Point | 203-204° |
| Solubility | Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in methylene chloride. |
| Appearance | neat |
| pKa | pKa 8.0 (Uncertain);9.8 (Uncertain) |
| Storage Condition | Inert atmosphere,2-8°C |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| In vitro study | Results show that Isoxsuprine hydrochloride inhibits circular chemorepellent induced defect (CCID) formation dose dependently (5 to 60 μM) and also inhibits 12(S)-HETE synthesis. Furthermore, Isoxsuprine hydrochloride is the only drug inhibiting the induction of all three mobility markers (MLC2, MYPT and paxillin). |
| In vivo study | Total infarct volume in vehicle-treated animals is 279±25 mm 3 compare to 137±18 mm 3 in Isoxsuprine hydrochloride-treated animals. |
Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI) - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R63 - Possible risk of harm to the unborn child R50 - Very Toxic to aquatic organisms |
| Safety Description | S36 - Wear suitable protective clothing. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S60 - This material and its container must be disposed of as hazardous waste. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| RTECS | DO8225000 |
| HS Code | 2922504500 |
| Toxicity | LD50 in rats (mg/kg): 1750 orally; 164 i.p. (Goldenthal) |
Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI) - Reference Information
| biological activity | isoxsupramine hydrochloride is a beta-adrenergic receptor (beta-adrenergic) agonist with vasodilator activity. |
| Target | Ki: 13.65 μm, 3.48 μm (placcntal beta-adreneric receptor) NMDA receptor |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 20:49:11
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Multiple Specifications
Product Name: ISOXSUPRINE HYDROCHLORIDE Visit Supplier Webpage Request for quotationCAS: 579-56-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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